Reinforcement of macroporous calcium phosphate cement scaffold by polymers infiltration

The macroporous calcium phosphate cement (CPC) scaffold was fabricated by dissolving the rod-shaped
 monosodium glutamate crystals. Gelatin,PLA,PCL,PLGA and PHBV solutions were infiltrated into the pores of a CPC scaffold to improve its mechanical strength. The results indicate that the contact angle of water on the polymers varies from each other in the sequence of PHBV > PCL > PLA > PL GA > Gelatin , and the compressive strength of the composite scaffolds increases with the increase of the hydrophilicity of the polymers. The CPC scaffold is markedly reinforced by the polymers infiltration except for PHBV,and the strength of Gelatin/CPC scaffold reaches 2. 25 MPa,which is 25 times that of CPC scaffold. The reinforced CPC scaffolds are promising for being used in the bone tissue engineering.