Volume 40 Issue 10
Oct.  2023
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GU Na, WANG Tiantian, LI Hong, et al. Activated chlorine-modified zirconium-based MOF composites for efficient bacterial inhibition[J]. Acta Materiae Compositae Sinica, 2023, 40(10): 5760-5771. doi: 10.13801/j.cnki.fhclxb.20230104.001
Citation: GU Na, WANG Tiantian, LI Hong, et al. Activated chlorine-modified zirconium-based MOF composites for efficient bacterial inhibition[J]. Acta Materiae Compositae Sinica, 2023, 40(10): 5760-5771. doi: 10.13801/j.cnki.fhclxb.20230104.001

Activated chlorine-modified zirconium-based MOF composites for efficient bacterial inhibition

doi: 10.13801/j.cnki.fhclxb.20230104.001
  • Received Date: 2022-10-25
  • Accepted Date: 2022-12-22
  • Rev Recd Date: 2022-12-05
  • Available Online: 2023-01-04
  • Publish Date: 2023-10-15
  • In recent years, serious industrial pollution has led to the growth of various types of bacteria, and pathogenic bacterial infections can be spread rapidly by various means, posing a great risk of infection. Therefore, it is important to develop high-performance antibacterial materials and study their antibacterial mechanisms for application. To address this issue, this work designed a novel nanocomposite bacteriostatic material UiO-66-NHCl by modifying zirconium-based metal-organic backbone material UiO-66-NH2 via sodium chlorite solution, and characterized the structure and chemical composition of metal-organic framework (MOF) composites by using XRD, FTIR, SEM, TEM, EDS and XPS, and the effects of different loading processes on the chlorine loading were also explored, and the antibacterial properties and skin irritation experiments of UiO-66-NHCl composites were investigated. The results show that the active chlorine is introduced on UiO-66-NH2 by impregnation bonding, and the chlorine loading can be increased by changing the chlorine loading ratio (mass ratios m(UiO-66-NH2)∶m(NaClO2)) and chlorination time of UiO-66-NH2 in NaClO2 solution, and the highest chlorine loading is achieved when the chlorine loading ratio is 1∶5 and the chlorination time is 4 h. Under the conditions of high temperature, high humidity and high temperature, it can still maintain 80% of its original chlorine loading and has good stability. The inhibition activity show that the UiO-66-NHCl composites inhibit both Staphylococcus aureus and Escherichia coli compared to the original UiO-66-NH2 material, and the samples with higher chlorine content show higher inhibition effect and no irritation.


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