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GE Jianhua, WANG Yingjun, CHEN Xiaofeng, et al. Degradable performance and bio-mineralization function of bioglass/PLA-PEG-PLA/poly(Lactic acid) tissue engineering scaffold in SBF[J]. Acta Materiae Compositae Sinica, 2013, 30(6): 96-100.
Citation: GE Jianhua, WANG Yingjun, CHEN Xiaofeng, et al. Degradable performance and bio-mineralization function of bioglass/PLA-PEG-PLA/poly(Lactic acid) tissue engineering scaffold in SBF[J]. Acta Materiae Compositae Sinica, 2013, 30(6): 96-100.
shu

Degradable performance and bio-mineralization function of bioglass/PLA-PEG-PLA/poly(Lactic acid) tissue engineering scaffold in SBF

  • 1.

    School of Materials Science and Engineering, Shandong University, Ji'nan 250061, China;

  • 2.

    School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China;

  • 3.

    Materials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China;

  • 4.

    Key Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), Shandong University, Ji'nan 250061, China

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  • Received Date: November 19, 2012
  • Revised Date: July 28, 2013
    Abstract
  • The degradable performance and bio-mineralization function of bioglass/poly(lactic acid)-poly(ethylene glycol)-poly(lactic acid) block copolymer (PLA-PEG-PLA)/poly(lactic acid) tissue engineering scaffolds were systematically studied in the simulated body fluid (SBF) by measuring pH value of SBF, the mass loss ratio of the scaffolds and analyzing SEM pictures, XRD and FTIR spectra of scaffolds' surface. The results show that in SBF, the pH value of SBF with tissue engineering scaffolds and the mass of scaffolds decrease with the prolongation of time. At the same time, the present of bioglass makes pH value of SBF increase and the present of PLA-PEG-PLA makes pH value of SBF decrease. SEM pictures, XRD and FTIR spectra show that there appears the deposition of carbonate hydroxyl apatite on the surface of the bioglass/PLA-PEG-PLA/poly(lactic acid) tissue engineering scaffolds, and the degradation rate of PLA-PEG-PLA is quicker than that of PLA in SBF, because the present of PLA-PEG-PLA in the sample immersed in SBF for 7 d could not be detected by FTIR.
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