Preparation of collagen modified bioactive glass/poly(<em>ε</em>-caprolactone) porous composites for bone tissue repairing

LUO Xiaogang; CHEN Xiaofeng; LI Yuli; SHEN Deyong; HU Qing; LIN Cai

doi:CNKI:11-1801/TB.20110720.1423.031

Volume 28 Issue 6

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LUO Xiaogang, CHEN Xiaofeng, LI Yuli, et al. Preparation of collagen modified bioactive glass/poly(ε-caprolactone) porous composites for bone tissue repairing[J]. Acta Materiae Compositae Sinica, 2011, 28(6): 98-103. doi: CNKI:11-1801/TB.20110720.1423.031

Citation:

LUO Xiaogang, CHEN Xiaofeng, LI Yuli, et al. Preparation of collagen modified bioactive glass/poly(ε-caprolactone) porous composites for bone tissue repairing[J]. Acta Materiae Compositae Sinica, 2011, 28(6): 98-103. doi: CNKI:11-1801/TB.20110720.1423.031

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Preparation of collagen modified bioactive glass/poly(ε-caprolactone) porous composites for bone tissue repairing

doi: CNKI:11-1801/TB.20110720.1423.031

LUO Xiaogang^1,2,
CHEN Xiaofeng^{1,2
,},
LI Yuli^1,2,
SHEN Deyong^1,2,
HU Qing^1,2,
LIN Cai^1,2,3

1.
National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510640, China;
2.
School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China;
3.
The First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, China

Received Date: 2010-11-24
Rev Recd Date: 2011-03-01
Publish Date: 2011-12-15

Abstract

Abstract

Bioactive glass(BG)/poly(ε-caprolactone)(PCL) porous composites modified by collagen for bone repairing were prepared by combining particulates-leaching and solvent-evaporation methods. The morphology of the porous materials and pore-wall, mineralization activity, ionic concentration and variation of pH values were characterized by SEM, FTIR, XRD, plasma atomic emission spectroscope and pH meter. The effects of colllagen on the porosity and water absorption rate were characterized by traditional specific-gravity and weighing methods. The results indicate that collagen can be succesfully adhered onto the pore wall and the mineralization activity and degradability of BG/PCL are effectively improved. Porosity and water absorption rate are as high as 96.400%±0.018% and 13.65±1.65, respectively.
- collagen,
- bioactive glass,
- poly(ε-caprolactone),
- modified,
- mineralization,
- degradability
Long Abstrsct
Innovation Points