Abstract: Lithium ion sieve formation technology for Li⁺ recovery industrial production and application from brine is very important. Polyvinyl chloride (PVC)-Li_1.6Mn_1.6O₄ lithium ion sieve precursor membrane was prepared by blend of Li_1.6Mn_1.6O₄ with PVC, polymethyl methacrylate (PMMA) and polyvinylpyrrolidone (PVP_k30). After the precursor membrane was treated with HCl solution it can uptake lithium. A series of experiments for examining its adsorption and cyclic performance were carried out. The adsorption isotherm model and the adsorption kinetics of PVC lithium ion sieve membrane were analyzed. The results showed that the adsorption capacity of PVC lithium ion sieve membrane was 1336.30 mg/m² when the concentration of PVC was 10wt%, the content of PMMA was 6wt%, the content of PVP_k30 was 2wt%, and the amount of loading of Li_1.6Mn_1.6O₄ was 20wt%. After treated with 0.1 mol·L⁻¹ HCl for 2 h, the lithium extraction reached equilibrium and the dissolution loss rate of Mn²⁺ was about 0.56%. After 10 cycles of adsorption and desorption in brine, the Li⁺ adsorption capacity was lost only 3.0% (from 1336.30 mg/m² to 1294.16 mg/m²). The PVC lithium ion sieve membrane showed great selectivity for Li⁺ in brine containing a variety of complex ions such as Na⁺, K⁺, Mg²⁺ and Ca²⁺. The PVC lithium ion sieve membrane has stable structure and excellent recycling performance, which is conducive to its industrial application. The PVC lithium ion sieve membrane accords with the pseudo second order kinetic equation and Langmuir adsorption isotherm model, indicating a monolayer chemisorption. It is potential to be used in enrichment and recovery of lithium from salt lake brine and other liquid lithium sources.