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纳米材料在电化学传感器检测抗生素中的应用进展

姚聪聪 魏坚强 林金玉 陆秋月 钱君超 陈丰

姚聪聪, 魏坚强, 林金玉, 等. 纳米材料在电化学传感器检测抗生素中的应用进展[J]. 复合材料学报, 2022, 40(0): 1-12
引用本文: 姚聪聪, 魏坚强, 林金玉, 等. 纳米材料在电化学传感器检测抗生素中的应用进展[J]. 复合材料学报, 2022, 40(0): 1-12
Congcong YAO, Jianqiang WEI, Jinyu LING, Qiuyue LU, Junchao QIAN, Feng CHEN. Application progress of nano-materials in detection of antibiotics by electrochemical sensors[J]. Acta Materiae Compositae Sinica.
Citation: Congcong YAO, Jianqiang WEI, Jinyu LING, Qiuyue LU, Junchao QIAN, Feng CHEN. Application progress of nano-materials in detection of antibiotics by electrochemical sensors[J]. Acta Materiae Compositae Sinica.

纳米材料在电化学传感器检测抗生素中的应用进展

基金项目: 江苏省自然科学基金(BK20180103);常熟市社会发展项目(CS202008);江苏高校水处理技术与材料协同创新中心预研课题资助
详细信息
    通讯作者:

    陈丰,博士,副教授,硕士生导师,研究方向为环境功能材料与催化材料 E-mail:chenfeng@mail.usts.edu.cn

  • 中图分类号: TB3333

Application progress of nano-materials in detection of antibiotics by electrochemical sensors

  • 摘要: 抗生素自发现至今,由于其可以阻碍细菌的生长,被广泛应用于预防和治疗细菌的感染疾病上。但是抗生素在畜牧业、农业等方面的滥用滥排导致抗生素污染,极大地威胁水源地的安全,导致细菌耐药性增强、给环境及人类健康带来重大的危害。因此,抗生素的检测近年来得到了广泛的关注,而大多抗生素都具有电化学活性。基于此,纳米修饰电极可以使抗生素在电解质中的电化学氧化或还原反应增强,从而促进其灵敏度的提高,使电化学传感器可以检测到各类抗生素。本文详细介绍了用于检测抗生素的各种纳米材料修饰电极的电化学传感器以及其性能。最后,讨论了纳米材料电化学传感器在抗生素检测中面临的挑战和发展前景。

     

  • 图  1  (A)铂纳米球制备示意图/GCE表面修饰;(B)裸GCE的SEM图像;(C)聚糠醛膜修饰GCE的SEM图像;(D)和(E)是铂纳米球/聚糠醛膜修饰GCE的SEM图像;(F)铂纳米球/聚糠醛膜/GCE的高倍SEM图像。(G)和(H)分别是(a)裸GCE, (b)铂纳米球/GCE, (c) 聚糠醛膜/GCE, (d)铂纳米球/聚糠醛膜/GCE, (f)裸铂电极, (e) 在不含甲硝唑的铂纳米球/聚糠醛膜/GCE。

    Figure  1.  (a) Preparation schematic diagram of platinum nanospheres /GCE surface modification; (b) SEM images of naked GCE; (c) SEM images of GCE modified by polyfurfural film; (d) and (e) are SEM images of GCE modified by platinum nanosphere/polyfurfural film; (f) High power SEM images of platinum nanospheres/polyfurfural films /GCE. (g) and (h) are (a) bare GCE, (b) platinum nanosphere /GCE, (c) polyfurfural membrane /GCE, (d) platinum nanosphere/polyfurfural membrane /GCE, (f) bare platinum electrode, (e) platinum nanosphere/polyfurfural membrane /GCE without metronidazole.

    图  2  GO/ZnO改性GCE制备示意图

    Figure  2.  Schematic diagram of GO/ZnO modified GCE preparation

    图  3  (A)是CdTe-CB-CTS的透射电子显微镜(TEM)图像;(B)透射电子显微镜中的放大图像;(C)和(D)显示了CdTe QDS的TEM图像;(E) a、b、c分别是裸GCE,CB-CT:EPH/GCE和CdTe CB-CT:EPH/GCE电极在0.1 mol L−1的磷酸盐缓冲液中,pH 6.0的条件下的CV曲线;(F) NOR的氧化反应

    Figure  3.  (a) is a transmission electron microscope (TEM) image of CdTe-CB-CTS; (b) Enlarged image in transmission electron microscope; (c) and (d) show TEM images of CdTe QDS; (E) a, B and C are naked GCE, CB-CT:EPH/GCE and CdTe CB-CT: CV curve of Eph/GCE electrode in 0.1 mol L1 phosphate buffer at pH 6.0; (f) Oxidation reaction of NOR

    图  4  用于检测AMP的MIPs EC传感器构造过程示意图

    Figure  4.  Schematic diagram of MIPs EC sensor construction process for detecting AMP

    图  5  GNPs和MIPs制备和检测过程示意图

    Figure  5.  Schematic diagram of preparation and detection process of GNPs and MIPs

    图  6  MoS2-TiO2@Au纳米材料的制备及检测示意图

    Figure  6.  Schematic diagram of preparation and detection of MoS2-TiO2 @ au nanomaterials

    表  1  常见抗生素

    Table  1.   Common antibiotics

    抗生素种类名称
    磺胺类[5]磺胺噻唑、磺胺甲恶唑、磺胺甲嘧啶、磺胺甲二唑等
    四环素类[6]四环素、土霉素、金霉素等
    大环内酯类[7]红霉素、罗红霉素、阿奇霉素、克拉霉素、地红霉素、氟红霉素、泰利霉素等
    β-内酰胺类[8]青霉素G、苯唑西林、氨苄西林、羧苄西林、哌拉西林、头孢唑啉、头孢呋辛、头孢噻肟、头孢吡肟等
    氨基糖苷类[9]链霉素、卡那霉素、新霉素、妥布霉素、庆大霉素、阿米卡星等
    喹诺酮类[10]氧氟沙星、培诺沙星、诺氟沙星还有环丙沙星等
    其他甲硝唑,万古霉素、林可霉素,克林霉素等
    下载: 导出CSV
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  • 收稿日期:  2022-02-14
  • 录用日期:  2022-04-03
  • 修回日期:  2022-03-24
  • 网络出版日期:  2022-04-18

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