Research status of Ag NPs composite antibacterial agent and its carriers
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摘要: 近年来,新型抗菌材料的开发受到了各领域的极大关注,抗菌技术的应用与人类的健康生活息息相关,有巨大的发展前景。纳米银系抗菌剂是目前应用最广泛的抗菌剂之一,本文对纳米银(Ag NPs)的抗菌机制进行了讨论,综述了Ag NPs无机抗菌剂与天然抗菌剂、有机抗菌剂和其他无机抗菌剂等复合的新型抗菌剂的研究进展,同时,从无机载体、有机载体和新型载体这3个方面对纳米银系抗菌剂的载体进行了总结,为Ag NPs抗菌剂的进一步研究与应用提供参考。Abstract: In recent years, the development of antibacterial materials has received great attention in various fields. The application of antibacterial technology is closely related to human health and has a great development prospect. Ag nanoparticles (Ag NPs) antibacterial agent is one of the most widely used antibacterial agents at present. In this paper, the antibacterial mechanism of Ag NPs antibacterial agent is discussed. Besides, the research progress of composite antibacterial agent composed of Ag NPs and natural antibacterial agent, organic antibacterial agent and inorganic antibacterial agent respectively is introduced. At the same time, the carrier of Ag NPs antibacterial agent was introduced from three aspects: Inorganic carrier, organic carrier and new carrier, which can provide reference for further research and application of Ag NPs antibacterial agent.
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Key words:
- Ag NPs /
- antibacterial agent /
- composites /
- nano-carrier /
- antibacterial material
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表 1 Ag NPs抗菌剂载体的分类、结构及负载方式
Table 1. Classification, structure and loading method of different Ag NPs carriers
Classification Common carriers Structure Load mode Ref. Inorganic carrier Zeolite Three-dimensional open architecture Physical adsorption, electrostatic
binding, covalent grafting[41, 46-47, 52] Montmorillonite 2∶1 lamellar structure Zirconium phosphate Layered structure Graphene oxide Carbon honeycomb structure Organic carrier Chitosan Linear network structure Physical adsorption, in situ reduction, macromolecular matrix effect [56, 59, 61] Liposomes A spherical vesicle with a bilayer
membrane structurePhysical coating Nano-cellulose Fibrous structure Physical adsorption, in situ reduction New carrier Mental organic framework Three-dimensional network structure
with metal ions as the centerSelf-assembly of metal ions, loading of porous structure [68-69] Microcapsule Core-shell structure In situ polymerization or deposition -
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