Abstract: The rapid hemostasis and healing of wounds after trauma hold great significance to solve the bleeding caused by accidents. Therefore, the development and application of related hemostatic materials have attracted much attention. Biomass-derived materials such as proteins including keratin, silk fibroin, collagen and polysaccharides including cellulose, chitosan, and alginic acid are favored by researchers because of their non-toxicity, low antigenicity, good biocompatibility, and biodegradability, and have shown unprecedented application value in the field of hemostasis. In this paper, the latest research results on the design, the preparation and the application of biomass hemostatic materials are comprehensively reviewed, and their development prospects are prospected, which will provide ideas for the development and practical application of new high-efficiency hemostatic materials.