Abstract: Magnetic-responsive dendritic mesoporous silica nanoparticles are composed of magnetic materials and mesoporous silica materials along with dendritic structural features. This kind of composite naturally possesses physicochemical properties of its constituent materials, like ultra-high specific surface area, super-large pore volume, and nanoscale effects from mesoporous silica as well as magnetic responsiveness from magnetic material, which enables intelligent control towards magnetic recovery and transfer. Consequently, magnetic-responsive dendritic mesoporous silica nanoparticles hold broad application prospects and advantages in multiple fields, like chemical adsorption of heavy metal and dye, organic catalytic synthesis and pollutant degradation, drug delivery and therapy, and so forth. Up to date, no review has been officially published with respect to specifically introducing magnetic-responsive dendritic mesoporous silica nanoparticles. This paper not only systematically categorizes magnetic-responsive dendritic mesoporous silica nanoparticles, but also analyzes their structural characteristics, preparation methods, and application domains. It also outlines future research priorities and development prospects in this field. It is expected that this review could serve as a reference for material and chemical scientists, accelerating the vigorous development of magnetic-responsive dendritic mesoporous silica nanoparticles.