Abstract: Glass fibers were surface treated with polymethylmethacrylate (PMMA) acetone solutions of various concent rations. The amount of PMMA on glass fiber，surface nature of glass fibers and the interfacial and mechanical properties of the treated glass fiber/dental resin composites were investigated. The results show that PMMA polymer adhered to the glass fiber surface and the amount of PMMA on the glass fiber surface increases with increasing concentration of PMMA solution. By controlling the mass fraction of PMMA on the glass fiber surface about 1%，a perfect semi-interpenet rating polymer network interface is formed between glass fiber and dental resin matrix. The flexural strength and flexural modulus of the treated glass fiber/dental resin composites increase by 29.6% and 30% after being treated with 5% PMMA solution，which could be used as a new bio-composite for dental restoration.