Abstract: Nanozymes are nanomaterials that mimic natural enzyme activity, combining the unique properties of nanomaterials with catalytic capabilities similar to those of natural enzymes. Among various nanozymes, metal-organic framework (MOFs) nanozymes, as a new type of biosensing material, have gained significant attention in food analysis. Metal-organic frameworks (MOFs) are an emerging class of porous crystalline materials known for their uniform structures, ultra-high porosity, tunable compositions, and easily functionalized surfaces. MOFs-based sensors have emerged as promising complementary or alternative tools to conventional detection methods due to their high absorbency, strong luminescent properties, and cost-effectiveness. This review summarises the properties and types of commonly used MOFs enzymes and explores their application s in the detection of pesticides, additives, heavy metals, harmful microorganisims and functional ingredients. Finally, we discuss the challenges faced by luminescent MOFs in complex ecviornments and outline propects for future development.