Abstract: The stringer-embedded honeycomb structure, which contains the advantages of both honeycomb structure and riveted structure, is an innovative structure improved from honeycomb. However, the relative research on load distribution and failure modes on this type of structure is inadequate. Depend on the largest aluminum honeycomb sandwich structure under researching, beam-reinforced laminate method was used for numerical simulation. Further to this, a full-size physical test was also designed. Good agreement has been achieved in the comparison between the numerical simulation and test, which verifies the beam-reinforced laminate method. This paper also investigated load distribution and failure modes of stringer-embedded honeycomb structure, and it can be regarded as a design reference for similar structure.