Abstract: To analyze the influence of phase change and plastic deformation under high temperature on inherent properties of metal honeycomb sandwich structure, a nonlinear coupling analysis was implemented to honeycomb sandwich structure equipped with heating elements by the finite element numerical solution method, which was based on transient heat transfer theory of multilayer panel with phase change and thermal elastoplastic theory. By means of the analysis on the temperature field, the solid-liquid and gas-liquid phase change occurred in outer glue, and the occurring time, location, severity, and development trends can be quickly determined. Combining with the computation results of temperature field and stress field, the plastic deformation produced in the outer skin can be easily confirmed, and its dynamic evolution laws versus loaded time can also be predicted.