电气石/壳聚糖复合纤维的表征及细胞相容性

赵凯; 肖建刚; 李峻峰; 李玉宝; 邹琴

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电气石/壳聚糖复合纤维的表征及细胞相容性

1.
四川大学材料科学与工程学院, 成都 610065;
2.
成都理工大学材料科学技术研究所, 成都 610059;
3.
四川大学分析测试中心, 纳米生物材料研究中心, 成都 610065

基金项目: 国家自然科学基金青年基金项目（51003008）

详细信息

通讯作者:
邹琴，博士，讲师，研究方向：生物医学工程 E-mail：zouqin80913@126.com

中图分类号: TB332;R318.08
计量
- 文章访问数: 601
- PDF下载量: 822
- 被引次数: 0
出版历程
- 收稿日期: 2012-11-28
- 修回日期: 2013-05-29
- 刊出日期: 2013-12-15

Characterization and cytocompatibility of tourmaline/chitosan composite fiber

1.
College of Materials Science and Engineering, Sichuan University, Chengdu 610065, China;
2.
Institute of Material Science and Technology, Chengdu University of Technology, Chengdu 610059, China;
3.
Research Center for Nano-Biomaterials, Analytical & Testing Center, Sichuan University, Chengdu 610065, China

摘要

摘要: 以壳聚糖为基体，电气石为分散相，采用溶液纺丝法制备电气石/壳聚糖复合纤维，利用光学显微镜、扫描电镜以及红外光谱仪对材料进行表征。电气石/壳聚糖复合纤维与人骨肉瘤细胞株（MG63）体外共培养，初步评价了材料的细胞相容性。结果显示，电气石颗粒在复合纤维中分散均匀且被壳聚糖包裹，纤维表面无裸露电气石。细胞在电气石/壳聚糖复合纤维表面黏附及生长增殖状况良好，材料对细胞无明显毒性。该材料有望成为一种良好的创伤修复敷料。
- 电气石 /
- 壳聚糖 /
- 复合纤维 /
- 溶液纺丝 /
- 细胞相容性
Abstract: Tourmaline/chitosan(Tur/CS) composite fibers were prepared with Chitosan as the matrix and tourmaline as the dispersed phase by solution spinning, and characterized by optical microscope, SEM and FTIR. MG63 cells were co-cultured with Tur/CS composite fibers to assess the cytocompatibility. The results show that the tourmaline particles were wrapped by chitosan and fully dispersed in the composite fiber. There were no bare tourmaline particles on the surface. Cytocompatibility test using MG63 revealed positive cell viability and proliferation over a period in vitro. And materials appeared no apparent toxicity. These results indicate that the material can be a kind of good wound repair dressing.
- tourmaline /
- chitosan /
- composite fiber /
- solution spinning /
- cytocompatibility