Abstract: In this paper, nanoscale bioactive glass particles with different morphologies were prepared through adding citric acid in a sol-gel process. The structure of as-prepared samples was characterized using specific surface area analysis apparatus、 SEM and TEM. The results indicate that just using citric acid as hydrolysis catalyst can easily control the nanostructure and morphology of bioactive glass and is in favor of preparing the bioactive glass with smaller particle size, larger specific surface area and pore volume. This procedure can serve a simple mean with low cost to produce nanoscale bioactive glass and control its morphology.