Abstract: In recent years, the development of antibacterial materials has received great attention in various fields. The application of antibacterial technology is closely related to human health and has a great development prospect. Ag nanoparticles (Ag NPs) antibacterial agent is one of the most widely used antibacterial agents at present. In this paper, the antibacterial mechanism of Ag NPs antibacterial agent is discussed. Besides, the research progress of composite antibacterial agent composed of Ag NPs and natural antibacterial agent, organic antibacterial agent and inorganic antibacterial agent respectively is introduced. At the same time, the carrier of Ag NPs antibacterial agent was introduced from three aspects: Inorganic carrier, organic carrier and new carrier, which can provide reference for further research and application of Ag NPs antibacterial agent.