Abstract: The high temperature baseline seal with hybrid structure of multiple materials is a novel porous composite, which is composed of thermal insulation core material, metal braided spring tube and ceramic fiber braided tube. It has excellent multi-functional performances, including flexibility, high temperature resistance, abrasion resistance and sealing. It is vital for improving the comprehensive performance of the hot end components, especially for the new generation of high-speed aircraft. Hybrid structure of multiple materials can take advantage of specific attributes of each material to enhance the performance of a product or introduce new functionalities. For the proposed high-temperature baseline, the inner core material plays a role on thermal insulation, and the intermediate superalloy braided spring tube play a dominative effect on the elastic deformation recovery during the dynamic seal condition, and the outer ceramic fiber tube makes a function on heat and wear resistance. The major problem of hybrid structure is emanated from the different property of each component material, the internal relationship between hybrid structure and performance regulation is still unclear. To end this, the characteristics of each component material and fabrication technology of high temperature baseline seal with hybrid structure of multiple materials are firstly introduced. Then, the current research on the theory and numerical model of high temperature baseline are sorted out and summarized. Once more, the main challenges for the key fabrication technology of high-temperature baseline seal and its service ability in the high-temperature and dynamic loading are expounded. Finally, the research development trend and engineering application potentials of novel high-temperature baseline seal with hybrid structure of multiple materials are prospected.