Abstract: In order to improve the utilization rate of active substances, chitosan-polyvinylpyrrolidone hydrogel film loaded with tea polyphenols with pH response was prepared by selecting chitosan, polyvinylpyrrolidone as the substrate, glycerin as plasticizer, glutaraldehyde as crosslinker and tea polyphenol as antioxidant. The microstructure of the film was characterized by SEM and FTIR, and the water vapor transmittance, mechanical properties, swelling, gel content and oxidation resistance of the film were tested, and then the release rate of tea polyphenols in hydrogel films under different pH values was determined, the pH responsiveness was explored, and the release law of tea polyphenols was determined by constructing a kinetic model. The results show that the interaction between the crosslinker and chitosan forms a stable hydrogel structure, while the addition of tea polyphenols further improves the crosslinking strength and more stable structure between the components. The addition of crosslinking agent and tea polyphenols improves the physical and chemical properties of the film as a whole, the water vapor transmittance of the hydrogel film is (0.159±0.010) g·mm/(m²·h·kPa), the tensile strength was (40.58±2.11) MPa, the elongation at break is 62.32%±3.50%, the swelling ratio at swelling equilibrium is 346.27%±3.16%, and the gel content is 87.94%±0.50%. Compared with traditional films, the antioxidant activity is nearly 5 times higher. The hydrogel film loaded with tea polyphenols can effectively respond to pH changes, when the pH value is smaller, the cumulative release rate of tea polyphenols is larger, compared with the Higuchi and Ritger-Peppas model, the release law of tea polyphenols is consistent with the first-order kinetic model. Chitosan-polyvinylpyrrolidone hydrogel film loaded with tea polyphenols can effectively realize the pH response release of tea polyphenols and other active substances, and has the potential to be used in the field of food packaging.