Abstract: A flexible strain sensor is a device that converts changes in external stress into electrical signals. It overcomes the shortcomings of traditional rigid sensors such as high hardness and poor human adaptability. As a wearable device, it has great development prospects in the field of human motion monitoring. However, in harsh conditions or extreme environments, there are still risks such as signal output distortion and easy corrosion. The superhydrophobic flexible strain sensor combines the water repellency, surface self-cleaning, anti-corrosion and anti-fouling of the superhydrophobic coating with the high ductility and high sensitivity of the flexible strain sensor, which enhances the performance of the sensor and broadens the applications in human motion monitoring. This paper reviews the basic performance parameters of superhydrophobic flexible strain sensors, the commonly used construction materials and construction methods as well as their functions and applications in human motion monitoring, and provides perspectives on this field.