Abstract: In order to solve the problem that there were few experimental studies on Goodman curve of composite materials in China, based on ABAQUS finite element method, Python language was used to program and calculate the fatigue strength of a new type of bullet train carbon fiber reinforced polymer (CFRP) composite equipment cabin skeleton according to Germanischer Lloyd (GL) specification Goodman curve. Through fatigue strength tests under different average stresses, the Goodman curve and the Goodman curve considering a certain safety factor were drawn and compared with the Goodman curve of GL specification. The results show that under the fatigue conditions stipulated in EN12663-1:2010¹³ and reffence14, the Goodman curve of GL specification is feasible for checking the fatigue strength of the CFRP composite equipment cabin skeleton of the new electric multiple units. The CFRP composite equipment cabin skeleton can meet the design requirements, but safety is considered. When the safety coefficient n=1.5 and n=2, the evaluation has certain risk.