Abstract: The interference-fit joint can improve the bearing capacity and sealing performance of carbon fiber reinforced epoxy resin composite (CFRP). However, the oversized thrust force will cause bending deflection and delamination, which severely impacts the safety of the products. The assembling process of CFRP laminates with interference-fit joint, such as drilling, installing and tightening, was analyzed. The interference-fit bolt installation process of CFRP laminates was divided into 4 stages. The mechanical behavior of each stage was analyzed in detail. The extrusion force and friction at the bolt bar and chamfer were modeled. The thrust force of the whole installation process was established based on the displacement boundary condition and stages. The interference-fit bolt installation process of CFRP laminates was experimented and simulated by ABAQUS, the radial stress distribution and thrust force curves were compared and analyzed. The results of the analytical model and simulation and experiment match well. This work lays the foundation for the study of joint delamination and optimization.