表面多孔Ti-羟基磷灰石/Ti-Ag生物梯度复合材料的制备与性能

Fabrication and properties of surface porous Ti-hydroxyapatite/Ti-Ag gradient biocomposites

  • 摘要: 采用放电等离子烧结技术制备表面多孔Ti-羟基磷灰石(HA)/Ti-Ag生物梯度复合材料,研究了不同HA含量对复合材料微观结构、界面结合、表面孔隙特征、力学性能及体外生物活性的影响及机制。结果表明,表面多孔Ti-HA/Ti-Ag复合材料中间基体合金主要由α-Ti和Ti2Ag相组成,表面多孔层主要由α-Ti和HA相组成,同时还存在少量CaO、CaTiO3、Ti5P3等反应相;表面多孔Ti-HA/Ti-Ag复合材料中间基体与表面多孔层形成稳定的冶金结合,但随着HA含量增加,反应相增多,界面结合变差,表面孔隙率和平均孔径呈增大趋势,导致平均抗压强度减小且弹性模量降低,因此过高的HA含量会导致材料力学性能下降;体外生物活性实验表明,表面多孔Ti-HA/Ti-Ag复合材料在人工模拟体液中浸泡7天后表面生成大量类骨磷灰石层,并且随着HA含量的增大,磷灰石形成能力明显增强。

     

    Abstract: The surface porous Ti-hydroxyapatite(HA)/Ti-Ag gradient biocomposites were prepared by spark plasma sintering technology. The effects of different HA contents on the microstructure, interface bonding, surface pore characteristics, mechanical properties and in vitro biological activity of the surface porous Ti-HA/Ti-Ag composites were investigated. The results show that the matrix alloys of the composites are mainly consisted of α-Ti and Ti2Ag phases. The surface porous layers are mainly consisted of α-Ti, HA phases and a few reaction phases of CaO, CaTiO3, Ti5P3. A stable metallurgical bonding on matrix alloys and surface porous layers of the composites could be observed. With increasing of HA contents, the reaction phases of surface porous layers are increased and the bonding degree of interface is deterioration. The average porosity and pore size of surface layers are appeared in a slowly increasing trend. As a result, the average compressive strength and compressive elastic modulus of the surface porous Ti-HA/Ti-Ag composites are decreased. Therefore, the mechanical properties of the composites are reduced at higher HA contents. In vitro bioactivity tests show that lots of bone-like apatite are deposited on the surface porous Ti-HA/Ti-Ag gradient biocomposites after soaking in SBF for 7 days and the apatite formation ability is significant enhanced with increasing of HA contents.

     

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