Abstract: The formula of hybrid effect coefficient for the fracture strain of glass fiber/carbon fiber (GF/CF) inter-ply hybrid composite laminates was improved with better dispersity formula. Based on the formula of hybrid effect coefficient and the mixing rule, the prediction method on the tensile strength of unidirectional inter-ply hybrid composite laminates was put forward. The progressive damage FEM of the tensile strength of multidirectional composite laminates was established, into which the formula of hybrid effect coefficient and the improvement of tensile strength of low-elongation fiber lamina were introduced. On this basis, the prediction method of the tensile strength of multidirectional inter-ply hybrid composite laminates was proposed. In the model, the stiffness degradation cases of progressive damage were also discussed. The results show that the computational results are well consistent with the test results as a whole, especially better for the computational results with considering hybrid effect. The larger stiffness degradation coefficient of matrix shows better results.