银基蒙脱土/壳聚糖的制备及性能

李田; 张媛媛; 宋智勇; 吴宏涛; 李树浩

银基蒙脱土/壳聚糖的制备及性能

1.
广东药学院医药化工学院, 中山 528458;
2.
广东轻工业职业技术学院食品系, 广州 510300;
3.
广东药学院药科学院, 广州 510006

基金项目: 广东省大学生创新创业训练计划项目(1057312021);广东药学院大学生创新实验项目

详细信息

中图分类号: TB332
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- 被引次数: 0
出版历程
- 收稿日期: 2012-08-21
- 修回日期: 2012-11-19
- 刊出日期: 2013-08-15

Preparation and characterization of Ag-montmorillonite/chitosan

1.
College of of Chemistry and Chemical Engineering, Guangdong University of Pharmacy, Zhongshan 528458, China;
2.
Department of Food, Guangdong Light Industry Technical College, Guangzhou 510300, China;
3.
College of Pharmaceutical Science, Guangdong Pharmaceutical University, Guangzhou 510006, China

More Information

Corresponding author: 李田,博士,讲师,研究方向:高分子及其复合材料 E-mail:phdlitian@163.com

摘要

摘要: 为了在改善壳聚糖(CS)抑菌性能的同时提高其强度, 将银基蒙脱土(Ag-MMT)在CS的醋酸溶液中通过溶液插层法制备了银基蒙脱土/壳聚糖(Ag-MMT/CS)。在模拟体液环境中测得的银离子释放性能显示Ag-MMT/CS中的银离子可以达到平稳缓慢释放; 通过最小抑菌圈法对Ag-MMT/CS进行抑菌性能测试, 结果表明, Ag-MMT/CS对金黄色葡萄球菌有良好的抑菌效果, 抑菌圈直径可达9.2 mm, 比CS增大50.6%, 抑菌率测试结果显示蒙脱土的加入有助于吸附并杀死更多的细菌; 动态热机械分析(DMA)测试结果显示, Ag-MMT/CS的储能模量最高可达3261 MPa, 比CS提高195%, 显示出良好的动态力学性能。
- 壳聚糖 /
- 银基蒙脱土 /
- 抑菌 /
- 动态力学性能 /
- 复合材料
Abstract: To obtain antibacterial chitosan with improved dynamic mechanic properties, the Ag-MMT was dispersed in chitosan solution dissolving in acetic acid to obtain nano Ag-MMT/CS composite via solution intercalation. The Ag⁺ ion can be released steady and slowly from Ag-MMT/CS in vitro release test in simulated fluid. The bacterial inhibition zone diameter of Ag-MMT/CS is 9.2 mm, which is 50.6% larger than that of CS, the result shows Ag-MMT/CS's good antibacterial activity against Staphylococcus aureus. And the inhibition ratio test result suggests the significant surface area and adsorption capacities of MMT help a lot to immobilize more bacteria on the surface and improve the antibacterial activity of Ag-MMT/CS. In the dynamic thermomechanical analysis (DMA) test, the storage modulus of Ag-MMT/CS is 3261 MPa, which exhibits remarkable increase (195% larger than CS) in mechanic property.
- chitosan /
- Ag-MMT /
- antibacterial activity /
- dynamic mechanic property /
- composite