Abstract: The conducting film based on chemical vapor deposition (CVD)-graphene/poly(3, 4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT-PSS) hybrid composites was prepared by using liquid-phase exfoliation method. The microstructure of the graphene/PEDOT-PSS hybrid composites was characterized by using atomic force microscope and SEM. The conduction mechanism of the as-fabricated graphene/PEDOT-PSS film was studied by using ultraviolet-visible absorption spectroscopy, X-ray photoelectronic spectroscopy and FTIR. The graphene/PEDOT-PSS film shows high electrical properties with a sheet resistance of approximate 8 Ω/□. The conjugation effect between graphene and thiophene in PEDOT main chain leads to a change of electron cloud density, which enhances the carrier delocalization of PEDOT main chain and results in the conductivity enhancement of the PEDOT. Furthermore, the conjugation effect leads to the increase of carrier density of graphene, which can enhance the conductivity of graphene/PEDOT-PSS composite.