LV Caixia, YAO Zihua. Preparation and characterization of nano-hydroxyapatite/ chitosan-chondroitin sulfate composite materials[J]. Acta Materiae Compositae Sinica, 2007, 24(1): 110-115.
Citation: LV Caixia, YAO Zihua. Preparation and characterization of nano-hydroxyapatite/ chitosan-chondroitin sulfate composite materials[J]. Acta Materiae Compositae Sinica, 2007, 24(1): 110-115.

Preparation and characterization of nano-hydroxyapatite/ chitosan-chondroitin sulfate composite materials

More Information
  • Corresponding author: YAO Zihua
  • Received Date: 2006-04-03
  • Rev Recd Date: 2006-06-21
  • Publish Date: 2007-02-15
  • Nano-hydroxyapatite/chitosan-chondroitin sulfate composites with different mass ratios were prepared through the co-precipitation method. The properties of these composites were characterized and analyzed by means of XRD, SEM, TGA and Universal Testing Machine. The change of the mineralization surface of the composite, pH and the concentration of system in the simulated body fluid were observed. The results show that the nano-hydroxyapatite/chitosan-chondroitin sulfate composites have small influence on the body microenvironment, a good mineralization effect on the surfaces and an excellent biocompatibility and osteoconduction property. The maximum compressive strength value is 42.3MPa at 50% HA. The n-HA/CS-ChS composite can meet the demand of reparation and substitution of osteo-tissue engineering and will be the load-bearing substitute to treat bone defects.

     

  • loading
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2228) PDF downloads(1599) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return