In order to investigate the degradation law of bonding performance of CFRP-clay brick interface under sulfate soaking environment, the test was conducted by accelerated corrosion of CFRP-clay brick specimens with 10% mass fraction of sulfate solution, and the material properties were measured, and the change law of bearing capacity and bonding strength of CFRP-clay brick interface was analyzed by collecting the parameters of strain and bearing capacity. The study shows that sulfuric acid immersion has no significant effect on the mechanical properties of CFRP sheet and resin adhesive, but has a significant effect on the compressive strength of clay brick, which decreases by 34.50% after 180d sulfate immersion. For the ultimate bearing capacity and bond strength of CFRP-clay brick interface, it is found that the width of CFRP has an effect on both the bearing capacity and bond strength of the interface, increasing the width of the interface can increase the bearing capacity of the interface, but the bond strength of the interface will decrease as a result, and the larger the bond width is, the more significant the degradation of the bond performance of the interface under the effect of continuous sulfate immersion. Based on the test, the comprehensive influence coefficient of sulfate is introduced and calculated in two different ways to establish the CFRP-clay brick interfacial bearing capacity relationship model considering the influence of continuous sulfate soaking. The model can predict the degradation of the CFRP-clay brick interface by continuous sulfate soaking.