Volume 40 Issue 3
Mar.  2023
Turn off MathJax
Article Contents
WANG Jin, BAI Bo, LUO Yu, et al. Preparation and photo-thermal controlled release properties of nanodiamond/yeast-chitosan composite microspheres[J]. Acta Materiae Compositae Sinica, 2023, 40(3): 1676-1685. doi: 10.13801/j.cnki.fhclxb.20220616.001
Citation: WANG Jin, BAI Bo, LUO Yu, et al. Preparation and photo-thermal controlled release properties of nanodiamond/yeast-chitosan composite microspheres[J]. Acta Materiae Compositae Sinica, 2023, 40(3): 1676-1685. doi: 10.13801/j.cnki.fhclxb.20220616.001

Preparation and photo-thermal controlled release properties of nanodiamond/yeast-chitosan composite microspheres

doi: 10.13801/j.cnki.fhclxb.20220616.001
Funds:  Shaanxi Provincial Key Research and Development Program of Science and Technology (211429220192); Natural Science Basic Research Program of Shaanxi Province (2021SF-497; 2022TD-04); Water Conservancy Science and Technology Project of Shaanxi Province (2015slkj-02); Basic Research Project of the Central Universities (CHD300102291403; CHD300102290103; CHD300102292903); Chang'an University Innovation and Entrepreneurship Training Program for College Students in 2021 (S202110710308)
  • Received Date: 2022-04-27
  • Accepted Date: 2022-06-03
  • Rev Recd Date: 2022-05-17
  • Available Online: 2022-06-16
  • Publish Date: 2023-03-15
  • It is important to develop high-performance functional photo-thermal materials and establish controlled drug release models for the development of intelligent transportation materials for pesticides. Herein, nanodiamond (DND) was employed to prepare novel nanodiamond/yeast-chitosan (DND/YS-CS) composite hydrogel microspheres which had a cross-linked network structure through alkali gelation method. The microstructure, mechanical resistance and photo-thermal conversion performance of the composites were investigated. Moreover, indole-3-butyric acid (IBA) was used as a model to discuss the loading and controlled drug release and reveal the photo-thermal controlled release mechanism of IBA by DND/YS-CS. The results show that the composite microspheres has good mechanical properties, and the water retention capacity of the composite microspheres with DND content of 2.0 mg/mL reached 70.5% and 74% after ultrasonication and centrifugation for 1 h, respec-tively. The maximum temperature of the composites can reach to 37.6℃ under one sunlight intensity, proving that the composites possess excellent photothermal conversion ability. The maximum adsorption of IBA is 41.73 μg/mg when the composites have a DND concentration of 1.2 mg/mL. Finally, the controled drug release pattern of the composites is in accordance with the Korsmeyer-Peppas model, which exhibits an obvious stimulus response behavior and an "on-off" pattern of drug release under light.


  • loading
  • [1]
    ZHAO M, ZHOU H, CHEN L, et al. Carboxymethyl chitosan grafted trisiloxane surfactant nanoparticles with pH sensitivity for sustained release of pesticide[J]. Carbohydrate Polymers,2020,243:116433. doi: 10.1016/j.carbpol.2020.116433
    MICHALIK R, WANDZIK I. A mini-review on chitosan-based hydrogels with potential for sustainable agricultural applications[J]. Polymers, 2020, 12(10): 2425.
    VAKILI M, RAFATULLAH M, SALAMATINIA B, et al. Application of chitosan and its derivatives as adsorbents for dye removal from water and wastewater: A review[J]. Carbohydrate Polymers,2014,113:115-130. doi: 10.1016/j.carbpol.2014.07.007
    QU B, LUO Y C. Chitosan-based hydrogel beads: Preparations, modifications and applications in food and agriculture sectors-A review[J]. International Journal of Biologi-cal Macromolecules,2020,152:437-448. doi: 10.1016/j.ijbiomac.2020.02.240
    LZA B, YW B, ZL A, et al. Characteristics of equilibrium, kinetics studies for adsorption of Hg(II), Cu(II), and Ni(II) ions by thiourea-modified magnetic chitosan microspheres[J]. Journal of Hazardous Materials,2009,161(2-3):995-1002. doi: 10.1016/j.jhazmat.2008.04.078
    MONVISADE P, SIRIPHANNON P. Chitosan intercalated montmorillonite: Preparation, characterization and cationic dye adsorption[J]. Applied Clay Science,2009,42(3-4):427-431. doi: 10.1016/j.clay.2008.04.013
    FENG D, BAI B, WANG H, et al. Enhanced mechanical stability and sensitive swelling performance of chitosan/yeast hybrid hydrogel beads[J]. New Journal of Chemistry,2016,40(4):3350-3362. doi: 10.1039/C5NJ02404H
    OMIDI S, PIRHAYATI M, KAKANEJADIFARD A. Co-delivery of doxorubicin and curcumin by a pH-sensitive, injectable, and in situ hydrogel composed of chitosan, graphene, and cellulose nanowhisker[J]. Carbohydrte Polymers,2020,231:115745. doi: 10.1016/j.carbpol.2019.115745
    WANG Y, LIU S, YU W. Functionalized graphene oxide-reinforced chitosan hydrogel as biomimetic dressing for wound healing[J]. Macromol Biosci,2021,21(4):e2000432. doi: 10.1002/mabi.202000432
    ZHANG L, BAI B, HU N, et al. Efficient 3D-interfacial solar steam generation enabled by photothermal nanodiamonds paint-coat with optimized heat management[J]. Applied Thermal Engineering,2020,171:115059. doi: 10.1016/j.applthermaleng.2020.115059
    MEI M, BAI B, ZHENG D, et al. Novel fabrication of a yeast biochar-based photothermal-responsive platform for controlled imidacloprid release[J]. RSC Advances,2021,11(32):19395-19405. doi: 10.1039/D1RA02143E
    ŌSAWA E. Monodisperse single nanodiamond particulates[J]. Pure and Applied Chemistry,2008,80(7):1365-1379. doi: 10.1351/pac200880071365
    ZHENG D, BAI B, XU X, et al. Fabrication of detonation nanodiamond@sodium alginate hydrogel beads and their performance in sunlight-triggered water release[J]. RSC Advances,2019,9(48):27961-27972. doi: 10.1039/C9RA03914G
    FRICK E M, STRADER L C. Roles for IBA-derived auxin in plant development[J]. Journal of Experimental Botany,2018,69(2):169-177. doi: 10.1093/jxb/erx298
    ZHENG D, BAI B, HE Y, et al. Synthesis and characterization of dopamine-modified Ca-alginate/poly(N-isopropylacrylamide) microspheres for water retention and multi-responsive controlled release of agrochemicals[J]. International Journal of Biological Macromolecules,2020,160:518-530. doi: 10.1016/j.ijbiomac.2020.05.234
    ZHENG D, BAI B, ZHAO H, et al. Stimuli-responsive Ca-alginate-based photothermal system with enhanced foliar adhesion for controlled pesticide release[J]. Colloids Surfaces B: Biointerfaces,2021,207:112004. doi: 10.1016/j.colsurfb.2021.112004
    LIU Y, SUI Y, LIU C, et al. A physically crosslinked polydopamine/nanocellulose hydrogel as potential versatile vehicles for drug delivery and wound healing[J]. Carbohydrate Polymers,2018,188:27-36. doi: 10.1016/j.carbpol.2018.01.093
    WANG L, LI B, XU F, et al. UV-crosslinkable and thermo-responsive chitosan hybrid hydrogel for NIR-triggered localized on-demand drug delivery[J]. Carbohydrate Polymers,2017,174:904-914. doi: 10.1016/j.carbpol.2017.07.013
    SONG R, ZHENG J, LIU Y, et al. A natural cordycepin/chitosan complex hydrogel with outstanding self-healable and wound healing properties[J]. International Journal of Biological Macromolecules,2019,134:91-99. doi: 10.1016/j.ijbiomac.2019.04.195
    CHEN X, ZHOU J, ZHANG Y, et al. Polydopamine-modified polyaniline/nanodiamond ternary hybrids with brain fold-like surface for enhanced dual band electromagnetic absorption[J]. ACS Applied Polymer Materials,2019,1(3):405-413. doi: 10.1021/acsapm.8b00127
    NIU B, JIA J, WANG H, et al. In vitro and in vivo release of diclofenac sodium-loaded sodium alginate/carboxymethyl chitosan-ZnO hydrogel beads[J]. International Journal of Biological Macromolecules,2019,141:1191-1198. doi: 10.1016/j.ijbiomac.2019.09.059
    LIU P, JIANG L, ZHU L, et al. Novel covalently cross-linked attapulgite/poly(acrylic acid-co-acrylamide) hybrid hydrogels by inverse suspension polymerization: Synthesis optimization and evaluation as adsorbents for toxic heavy metals[J]. Industrial & Engineering Chemistry Research,2014,53(11):4277-4285.
    SIANGSANOH C, UMMARTYOTIN S, SATHIRAKUL K, et al. Fabrication and characterization of triple-responsive composite hydrogel for targeted and controlled drug delivery system[J]. Journal of Molecular Liquids,2018,256:90-99. doi: 10.1016/j.molliq.2018.02.026
    REINA G, ORLANDUCCI S, CAIRONE C, et al. Rhodamine/nanodiamond as a system model for drug carrier[J]. Journal of Nanoscience and Nanotechnology,2015,15(2):1022-1029. doi: 10.1166/jnn.2015.9736
    NAZLI A B, AÇIKEL Y S. Loading of cancer drug resveratrol to pH-sensitive, smart, alginate-chitosan hydrogels and investigation of controlled release kinetics[J]. Journal of Drug Delivery Science and Technology,2019,53(8):101199.
    DONG X, WEI C, LIANG J, et al. Thermosensitive hydrogel loaded with chitosan-carbon nanotubes for near infrared light triggered drug delivery[J]. Colloids and Surfaces B: Biointerfaces,2017,154:253-262. doi: 10.1016/j.colsurfb.2017.03.036
    WU W, WAN M, FEI Q, et al. PDA@Ti3C2Tx as a novel carrier for pesticide delivery and its application in plant protection: NIR-responsive controlled release and sustained antipest activity[J]. Pest Management Science,2021,77(11):4960-4970. doi: 10.1002/ps.6538
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(8)  / Tables(1)

    Article Metrics

    Article views (987) PDF downloads(42) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint