Research progress of nano-hydroxyapatite and its composite materials as drug carriers

Ying LU; Xiaowei XUN; Zhiwei YANG; Honglin LUO; Yizao WAN; Guifu ZUO

doi:10.13801/j.cnki.fhclxb.20200814.002

Volume 37 Issue 12

Dec. 2020

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Ying LU, Xiaowei XUN, Zhiwei YANG, Honglin LUO, Yizao WAN, Guifu ZUO. Research progress of nano-hydroxyapatite and its composite materials as drug carriers[J]. Acta Materiae Compositae Sinica, 2020, 37(12): 2953-2965. doi: 10.13801/j.cnki.fhclxb.20200814.002

Citation:

Ying LU, Xiaowei XUN, Zhiwei YANG, Honglin LUO, Yizao WAN, Guifu ZUO. Research progress of nano-hydroxyapatite and its composite materials as drug carriers[J]. Acta Materiae Compositae Sinica, 2020, 37(12): 2953-2965. doi: 10.13801/j.cnki.fhclxb.20200814.002

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Research progress of nano-hydroxyapatite and its composite materials as drug carriers

doi: 10.13801/j.cnki.fhclxb.20200814.002

Ying LU^1
,,
Xiaowei XUN^1
,,
Zhiwei YANG^1
,,
Honglin LUO^1
,,
Yizao WAN^1
,,
Guifu ZUO^{2
,
,}

1.
Jiangxi Provincial Key Laboratory of Nanometer Biomaterials, Institute of Advanced Materials, East China Jiaotong University, Nanchang 330013, China
2.
School of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, China

Received Date: 2020-06-22
Accepted Date: 2020-08-13

Available Online: 2020-08-14

Publish Date: 2020-12-15

Abstract

Abstract

Nano-hydroxyapatite (HAp) is an ideal inorganic drug carrier due to its good biological activity and drug adsorption ability. In this paper, the drug loading performance of nano-HAp was described by three aspects: Biological safety, antitumor activity and drug adsorption. Moreover, the effect of HAp micromorphology on drug-loading performance was also discussed. Furthermore, the classification, preparation, drug loading and drug release of nano-HAp composites were systematic reviewed, which aimed to provide a theoretical basis for application as drug carrier of nano-HAp and its composites.
- nano-hydroxyapatite,
- drug carrier,
- composite materials,
- micro-morphology,
- drug adsorption/release
Long Abstrsct
Innovation Points

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References(65)

References

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