Abstract: Based on the principle of bionics, a fish scale like flexible laminated protective device was built. The bionic scale is a double-layer composite with thick central region and thin edges. The upper and lower layers of the bionic scale were made of SiC ceramic and ultra-high molecular weight polyethylene (UHMWPE), respectively. The explicit analysis method in the ANSYS LS-DYNA software was used to simulate the ballistic performance of the SiC-UHMWPE flexible laminated structure. The analysis included the deformation, stress transfer pattern and energy dissipation mechanism of the device and the residual velocity of bullet, and mainly focused on the effects of the number of support points, the radius of curvature and the overlapping angle. The simulated backface signatures for the protective device with one row scales and multiple rows scales are 32.52 mm and 24.73 mm, respectively. Ballistic tests were conducted on the bio-inspired flexible protection device according to the requirements of level Ⅲ of the NIJ standard. The results show that there is an unfavorable mode of two-point support at the local area after multiple impacts of bullets. This study will be valuable for the design and manufacture of new flexible protective devices.