All specimens of MoS
2 and carbon fiber reinforced polyamide 1010(PA1010) composites were prepared by a micro injection machine. The friction coefficient and wear rate of composites were investigated with the ring-block test rig. The results show that hybrid fillers can considerably improve the tribological properties of PA1010 composites under dry sliding friction conditions. The dominant wear mechanisms of composites were abrasive wear and fatigue wear at a low normal pressure; the fatigue cracking and peeling due to thermal effect resulted in the severe wear of composites with the increase of normal pressure. The tribochemical reactions between MoS
2 and counterface Fe were found to generate FeS
2 and FeSO
4 which were more effective to promote the adhesive strength to the counterpart, and also MoS
2 was partially oxidized to MoO
3 during sliding.